Trailing 24-14, Middletown got within a field goal on a 15-yard touchdown run by Lemond Chambers.
That set up the game-winning score -- a touchdown pass from Davis to James Franklin.
Davis tossed a TD pass to DeMarco Powell and the quarterback also rushed for a 3-yard score.
Next up for Middletown is trip to Colerain next Friday night.
Sycamore (0-6, 0-5) hosts Lakota East next Friday.