It’s unclear what caused the tractor-trailer to hit the overpass.
Traffic cameras show major backups in the area, and police estimated it would affect northbound traffic for hours.
Earlier Wednesday, Southbound I-75 was shutdown at the Ezzard Charles Drive exit, during rush hour, after a pedestrian was struck on the highway, Cincinnati police said.
Police made southbound highway traffic take a detour at Ezzard Charles Drive. The crash was between Ezzard Charles Drive and Freeman Avenue.
Police did not provide an update on the condition of the person struck, nor did they say what type of vehicle is involved.
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