Antonio Banderas appears to have a role in the film as an antagonist to Dolittle, while Octavia Spencer, Kumail Nanjiani, Ralph Fiennes, Emma Thompson, John Cena, Selena Gomez and Downey Jr.'s Marvel co-star Tom Holland lend their voice talents.
Downey Jr. executive produces the film, which will be released Jan. 17, 2020.
Watch the trailer below.
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