Here are seven wrong-way crashes that happened in this part of the state since 2012.
2012: Fairfield man, son among 4 killed
Joshua Nkansah, 40, of Fairfield, was found to have a blood-alcohol content of .346, when Ohio State Highway Patrol said he caused a crash that killed him and three others, including his 7-year-old son, on Dec. 23, 2012.
Investigators said Nkansah began driving his 1997 Dodge minivan the wrong way on Interstate 75, near milepost 35 in Warren County. He struck a 2000 Chrysler minivan head-on, killing Michelle and Scott Barhorst of Madisonville, Tenn.
Nkansah and his son, David, 7, also were killed in the crash.
MORE: Driver in fatal crash had elevated blood-alcohol level
2014: Driver in single-vehicle crash dies
Reginald “Reggie” Mack Sr., 59, of Middletown, was driving a 1994 Ford F-150 the wrong direction on Roosevelt Boulevard around 12:30 a.m. Aug. 14, 2014, when he went over the grassy median, striking a tree head-on, according to the state patrol.
Mack was taken to Atrium Medical Center, where he was pronounced dead, investigators said. He was not wearing a seat belt, and alcohol is suspected to be a factor in the crash.
Mack was the only person in the vehicle, and no one else was injured.
MORE: Man drives wrong direction, hits tree in fatal crash
2016: Woman drove several miles wrong way
A woman accused of driving the wrong way on Interstate 71 when she caused a fatal, head-on crash in February 2016 pleaded guilty two months later to aggravated vehicular homicide, according to our media partner, WCPO-TV.
Taryn Chin, 22, of Cincinnati, was driving a minivan northbound in the southbound lanes when she struck a car driven by Jose Arenas Perez, 47, around 3 a.m. Feb. 17, 2016, according to police investigators. The crash happened just south of the Dana Avenue exit in Cincinnati. Police said Chin had driven south in northbound lanes before heading north in southbound lanes.
Perez, of Florence, Kentucky, was on his way home from work at Cintas. He died at the scene. Chin suffered only minor injuries and was treated at the scene, according to WCPO.
2016: Parents of 4 killed in wrong-way accident
A Fairfield couple died April 8, 2016, when a wrong-way driver, who also died, struck their car on I-75 in Evendale.
Nazif Shteiwi, 61, and his wife, Halla Odeh Shteiwi, 55, were returning from a family function in Kentucky when they were hit by Kory Wilson, 30, of Springfield Twp.
Wilson had a blood-alcohol level 2.5 times the legal limit in Ohio, the Hamilton County Coroner’s Office said. Witnesses said Wilson was driving the correct way on I-75 seconds before the crash, then abruptly turned around.
The Shteiwis, parents of four adult children, immigrated from Jordan 40 years ago, the family said.
MORE: Coroner: Driver drunk in crash that killed Fairfield couple
2016: Two transported to hospital following wrong-way crash
Police say alcohol was a factor in a May 2016 early morning wrong-way crash in Sharonville.
Kayla Chenault, 23, was driving the wrong way on eastbound Interstate 275 at Mosteller Road when she struck a white box truck, Sharonville police said told our news parnters, WCPO-TV.
Both Chenault and the box truck driver, 38-year-old Derrick Beverly, were injured in the crash and taken to University Hospital.
Chenault was transported by medical helicopter, but her condition later stabilized, police said.
2016: Rumpke truck catches fire
Springdale police said the driver going the wrong way on the highway crashed into a Rumpke truck in the early morning hours in August 2016, according to our media partners WCPO.
The vehicles collided head-on along westbound Interstate 275 near Ohio 747 at about 2:45 a.m., according to the Springdale Police Department. The Rumpke truck then caught fire.
The driver of the Rumpke truck went to Mercy Health-Fairfield for treatment.
The driver of the other vehicle went to University of Cincinnati Medical Center with serious injuries.
The crash closed westbound I-275 at Interstate 75 for several hours.
2018: Stolen vehicle crashes heading wrong way in highway
In June 2018, police told our news partner, WCPO, the driver of a stolen vehicle headed the wrong way on Ronald Reagan Highway drove upwards of 115 mph before crashing the car with three children.
Police said Ahkeela McCray, 26, of Avondale, and MIyoshi Flowers, 25, of West Price Hill, were fleeing after allegedly robbing a store at Northgate Mall in Springdale. They fled in a stolen vehicle.
The kids were OK after being treated at the scene, police said.
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